2024 Trend Updates: What Really Works In SEO & Content MarketingSearch Engine Journal
21 slides•648.1K views
The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready?
Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. We’ll dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust.
You’ll hear:
- The top SEO trends to prioritize in 2024 to achieve long-term success.
- Predictions for SGE’s impact, and how to adapt.
- What E-E-A-T really means, and how to implement it holistically (hint: it’s never been more important).
With Zack Kadish and Alex Carchietta, we’ll show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates.
If you’re looking to cut through the noise of constant SEO and content trends to drive success, you won’t want to miss this webinar.
Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta
39 slides•532.5K views
In this slides I explain how I have used storytelling techniques to elevate websites and brands and create memorable user experiences. You can discover practical tips as I showcase the elements of good storytelling and its applied to some examples of diverse brands/projects..
This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp.
This presentation was uploaded with the author’s consent.
How to Leverage AI to Boost Employee Wellness - Lydia Di Francesco - SocialHR...SocialHRCamp
28 slides•164K views
Speaker: Lydia Di Francesco
In this workshop, participants will delve into the realm of AI and its profound potential to revolutionize employee wellness initiatives. From stress management to fostering work-life harmony, AI offers a myriad of innovative tools and strategies that can significantly enhance the wellbeing of employees in any organization. Attendees will learn how to effectively leverage AI technologies to cultivate a healthier, happier, and more productive workforce. Whether it's utilizing AI-powered chatbots for mental health support, implementing data analytics to identify internal, systemic risk factors, or deploying personalized wellness apps, this workshop will equip participants with actionable insights and best practices to harness the power of AI for boosting employee wellness. Join us and discover how AI can be a strategic partner towards a culture of wellbeing and resilience in the workplace.
2024 State of Marketing Report – by HubspotMarius Sescu
43 slides•121.8K views
https://www.hubspot.com/state-of-marketing
· Scaling relationships and proving ROI
· Social media is the place for search, sales, and service
· Authentic influencer partnerships fuel brand growth
· The strongest connections happen via call, click, chat, and camera.
· Time saved with AI leads to more creative work
· Seeking: A single source of truth
· TLDR; Get on social, try AI, and align your systems.
· More human marketing, powered by robots
ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!
Product Design Trends in 2024 | Teenage EngineeringsPixeldarts
8 slides•52.4K views
The realm of product design is a constantly changing environment where technology and style intersect. Every year introduces fresh challenges and exciting trends that mold the future of this captivating art form. In this piece, we delve into the significant trends set to influence the look and functionality of product design in the year 2024.
How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow
21 slides•38.1K views
Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits.
To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups.
Technology
For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did.
While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis.
Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad.
Age and Gender
When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same.
Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers.
Race Affects Attitudes
As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).
New Drug Development in the Treatment of Ovarian Cancer: Future Perspectives
Ovarian cancer remains a major challenge in gynecologic oncology due to its late diagnosis, high relapse rate, and limited long-term treatment success. While surgery and platinum-based chemotherapy remain the mainstays of therapy, advances in molecular biology and precision medicine are transforming the treatment landscape. The future of ovarian cancer management lies in the development of targeted therapies, immunotherapy, and innovative drug delivery systems, aiming for personalized and durable outcomes.
PARP inhibitors have been among the most significant breakthroughs, particularly in patients with BRCA mutations or homologous recombination deficiency (HRD). Agents like olaparib, niraparib, and rucaparib work by exploiting defects in DNA repair mechanisms, leading to synthetic lethality in tumor cells. Their use has expanded from treatment of recurrent disease to maintenance therapy in first-line settings. Current research focuses on overcoming resistance by combining PARP inhibitors with other agents, such as immune checkpoint inhibitors, anti-angiogenic drugs, or ATR inhibitors.
Immunotherapy has had modest results in ovarian cancer so far, likely due to the immunosuppressive tumor microenvironment. However, future strategies are exploring combinations of checkpoint inhibitors (like pembrolizumab or nivolumab) with chemotherapy, PARP inhibitors, or anti-VEGF agents to enhance tumor immunogenicity. Additionally, experimental approaches such as CAR-T cells, oncolytic viruses, and cancer vaccines are under investigation.
Angiogenesis inhibitors, such as bevacizumab, have shown clinical benefit and are approved in both first-line and recurrent disease settings. Novel anti-angiogenic agents and combination regimens aim to further exploit the tumor’s reliance on blood supply while improving drug delivery and immune cell access.
Emerging therapies like antibody-drug conjugates (ADCs) offer targeted cytotoxicity by linking monoclonal antibodies to chemotherapy agents. Mirvetuximab soravtansine, targeting folate receptor alpha (FRα), is a leading ADC showing promise in platinum-resistant ovarian cancer.
Epigenetic therapies are another exciting avenue. Agents that modify DNA methylation or histone acetylation may reverse chemoresistance and sensitize tumors to other treatments. Similarly, targeting hormonal pathways and metabolic dependencies (like glucose and lipid metabolism) offers potential in select subtypes.
Looking ahead, the integration of genomic profiling, biomarkers, and artificial intelligence is driving a shift toward precision oncology. Techniques like liquid biopsy allow real-time monitoring of tumor evolution and therapeutic response. Moreover, advances in nanotechnology and local drug delivery systems are improving the precision and tolerability of therapies.
In conclusion, the future of ovarian cancer treatment is bright, with a strong focus on indi
Title: Iron and Hemoglobin Metabolism
Lecturer: Dr. Faiza
Assistant Professor of Physiology
Institution: [Your Institution's Name]
Description:
This lecture provides a thorough exploration of the essential processes involved in iron metabolism and the synthesis, function, and types of hemoglobin, with a specific focus on their roles in erythropoiesis. Dr. Faiza, Assistant Professor of Physiology, takes students through the biochemistry and physiology underlying these critical aspects of human biology. The lecture also delves into the importance of vitamin B12 and folic acid in red blood cell (RBC) maturation and the impact of iron metabolism on erythropoiesis.
Key learning objectives include:
Understanding the crucial roles of Vitamin B12 and Folic Acid in RBC maturation and their relationship with DNA synthesis.
Identifying the synthesis process and functions of Hemoglobin.
Analyzing the different types of hemoglobin and their relevance at various stages of human development.
Exploring iron metabolism, its role in the production of hemoglobin, and its essential involvement in erythropoiesis.
Discussing the metabolism of bilirubin and its clinical implications, including the development of jaundice.
The presentation also covers the important aspects of hemoglobin electrophoresis, the reversible binding of oxygen to hemoglobin, and its ability to transport carbon dioxide and nitric oxide, contributing to blood pressure regulation. Additionally, the lecture touches on metabolic disorders such as methemoglobinemia, where the iron in hemoglobin is oxidized, impairing oxygen binding.
Topics Covered:
Vitamin B12 and Folic Acid in RBC Maturation: The lecture emphasizes the role of these vitamins in DNA synthesis, with a focus on how deficiencies can lead to macrocytic anemia.
Hemoglobin Structure and Synthesis: Understanding the components of hemoglobin, including the globin chains and heme groups, and their formation process.
Types of Hemoglobin: Insight into embryonic, fetal, and adult hemoglobins, including the clinical significance of variants like HbS (sickle cell hemoglobin).
Iron Metabolism: A detailed look at how iron is absorbed, transported, and stored in the body, as well as its critical role in the production of hemoglobin.
Bilirubin Metabolism: The process of bilirubin production from RBC breakdown, including its implications for jaundice.
This lecture is designed to provide students with a deep understanding of these fundamental physiological processes, preparing them for clinical challenges and further studies in the field of hematology and physiology.
A vivid description of the acetate mevalonate pathway, a gateway for many secondary metabolites among which are volatile oils, saponins, and cardiac glycosides.
This particular document shows the origins of monoterpenes, diterpenes, sesquiterpenoids, triterpenoids and tetraterpenoids.
Ethical Concerns in Regenerative Medicine and Tissue Engineering: A Course Le...ajefferi
10 slides•231 views
A course learning resource for a new proposed course on ethical concerns in regenerative medicine and tissue engineering. Created by postgraduate students at University of Edinburgh.
Spinal biomechanics involves the regional features of the vertebrae, intervertebral discs, ligaments, facet joints and muscles. The role of these structures individually and in concert in relation to injuries.
Dr Aliya S.M
GIST , pathophysiology , diagnosis and management dr. amrish .pptxDr. Amrish Yadav
35 slides•66 views
1) Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the Gl tract that arise from interstitial cells of Cajal.
2) GISTs most commonly occur in the stomach and small intestine and present with Gl bleeding, abdominal pain, or mass.
3) Diagnostic workup includes CT, endoscopy, and biopsy to establish a diagnosis, assess resectability, and identify mutations for targeted therapy.
4) Complete surgical resection is the main treatment, while adjuvant imatinib therapy helps maintain remission and unresectable tumors may be downstaged with neoadjuvant imatinib
Bone mineral density measurements in nuclear medicineMiadAlsulami
39 slides•256 views
In every Nuclear Medicine department, DEXA scans are important and performed daily. It's crucial for us to accurately understand and interpret these scans.
Biophysics – Unit 01: Thermodynamics
This unit introduces the fundamental principles of thermodynamics and their application in biological and physiological systems. It explores how energy is exchanged and transformed in the human body, forming the basis of many critical clinical processes.
Key Concepts Covered:
System & Surroundings: Open, closed, and isolated systems relevant to physiological environments (e.g., respiratory system as an open system).
Zeroth Law: Basis for clinical thermometry and body temperature regulation.
First Law of Thermodynamics (Law of Energy Conservation): Application in calorimetry, metabolic rate calculation, and ATP energy balance.
Second Law of Thermodynamics: Directionality of biological processes, entropy, and energy efficiency in muscle contraction and enzymatic activity.
Third Law: Conceptual relevance in absolute zero and physiological limits.
Clinical Applications:
Energy transformations during cellular respiration
Thermal regulation and homeostasis in patients
Bioenergetics in critical care (e.g., post-operative energy needs, fever metabolism)
Use of thermodynamic principles in medical devices (ventilators, incubators, dialysis machines)
Negligence & Medical Ethics – The Unspoken Pandemic Presented by Dr. Kadiyali M Srivatsa
Every day, patients walk into clinics, trusting someone will care for them. But what if I told you…
that medical errors are now the third leading cause of death in the world?
Yes—after heart disease and cancer.
And the tragedy?
Most of these deaths are preventable.
🎬 Scene 2: Medical Negligence – A Global Crisis
On Screen:
⚠️ FACT: 2.6 million deaths annually are linked to medical errors – WHO
Narration:
According to the World Health Organization,
over 2.6 million people die every year due to unsafe medical care.
In high-income countries,
1 in 10 patients is harmed while receiving hospital care.
In low- and middle-income countries…
the number is likely even higher, but underreported.
This… is a silent pandemic.
Act of Commission vs. Omission
Negligence isn’t always about what’s done. It’s often about what is not done.
Doing what shouldn’t be done. Or…
failing to do what must be done.
Both destroy lives.
Nurses Acting as Doctors
Untrained, Unsupervised, Unethical. In some systems, nurses with only 6 months of training diagnose, prescribe, and manage patients without supervision.
This is not progress. It’s cost-cutting at the cost of lives.
Since 2006, hospitals in the UK began replacing doctors with “Independent Nurse Practitioners and prescriber.”
And what happened?
Avoidable deaths doubled. Medical litigation rose to £1.5 billion. Hospitals started collapsing under the weight of compensation claims.
Real Cases – Real Suffering
On Screen:
🚨 True Stories That Shake the Soul
Narration:
A nurse tells a 23-year-old woman with yellow eyes “It’s just a flu. Take paracetamol.” Two days later, she’s in liver failure.
A young man misdiagnosed with shingles actually has septicemia—He collapses in shock. Survives—but just barely.
A toddler with pneumonia is sent home. Told to return after the weekend.
She nearly dies. These are not accidents.
These are acts of negligence. And behind every mistake… is a family left grieving.
Why did I create Dr. Maya GPT?
Dr. Maya GPT – A Global Guardian for Patient Safety. I could no longer bear to watch patients suffer due to systemic negligence,
corporate cost-cutting, and ego-driven medicine.
Dr. Maya is not a replacement for doctors.
It is a guide.
A safety net.
An AI-powered guardian that helps people identify when to seek help—
and most importantly, whom to trust.
The Ethical Compass – Diligence - A Universal Virtue Across Faiths
Whether it's the teachings of the Bible, the Quran, the Gita, or the Dhammapada -they all echo one truth:
“Act with diligence.” That means effort. Integrity.
And doing the right thing—even when no one is watching.
This presentation is based on the series and flowcharts decisions to be made and of methods when dealing with a case of tooth avulsion in children (more specifically) and adults.
All references have been enumerated in the last slides.
Hit LIKE if you found this content helpful.
Genes are formed by the order of the nitrogenous bases present in the DNA which is crucial for protein synthesis. RNA is another nucleic acid that translates genetic information into proteins from DNA. The nucleotides are linked together for the formation of two long strands. genomics, which encompasses the examination of an organism's entire set of genetic material, including DNA and RNA.
by Dr Aliya S.M
BUMHS,QTA
Spondyloepiphyseal dysplasia is a mimicker of arthritisRitasman Baisya
11 slides•72 views
Musculoskeletal involvement in children is often challenging, with a wide range of benign conditions, such as growing pain, to severe systemic diseases. Spondylo-epiphyseal dysplasia (SED) is an autosomal recessive disease of the skeletal system that often mimics juvenile idiopathic arthritis (JIA) with no response to anti-rheumatic therapy.
Case - A young male, 22 years of age, presented with a history of pain in his upper and lower back and multiple small and large joints since five years of age. He denied any morning stiffness or increased nocturnal pain. Previously, he was treated outside as juvenile idiopathic arthritis with methotrexate, sulfasalazine and injection Adalimumab. However, his mother denied any symptomatic improvement of his pain. On examination, his growth was stunted with significant kyphoscoliosis. (Figure 1 ) He had an antalgic gait with exaggerated lumbar lordosis. He had mild tenderness in both hips, knees and ankles with flexion contracture and bony swelling at bilateral proximal & distal interphalangeal joints (PIP and DIP), referred to as camptodactyly. (Figure 2 ) His cervical and lumbar movement was severely restricted, with bilateral hip movement restricted. Laboratory investigation showed normal ESR CRP. Rheumatoid factor was low titre positive, anti-CCP antibody and HLA-B27 by PCR were negative. His skeletal radiographic images showed platyspondyly in the thoracolumbar spine, epiphyseal widening in MCP and IP joints with ovoid carpal bones (Figure 3), platyspondyly in the thoracolumbar spine (Figure 4) , hip joint sclerosis . (Figure 5 ) His diagnosis was reconsidered as spondyloepiphyseal dysplasia (SED) . He was started with extensive physiotherapy and symptomatic pain relief treatment and noticed improvement in his pain and quality of life.
Brief discussion - SED predominantly involves articular cartilage, which results in joint stiffness and epiphyseal enlargement. Typically starting at 2-8 years of age, they manifest with pain, stiffness and swelling of extremity joints. (1) On examination, the swelling is predominantly bony without any evidence of inflammation. Over time, the large joints and the spine get involved, causing significant joint contractures, gait abnormality, kyphoscoliosis, abnormal posture and poor quality of life. There are reported cases where SED have been misdiagnosed as JIA with no response to immunomodulatory treatment. (1,2) SED's radiological features differ from JIA, with platyspondyly being an early finding in the skeletal image, epiphyseal enlargement, and lack of destructive joint erosions. Though SED is considered a rare entity, one large study by Dalal et al. (3) reported 35 cases of SED from 25 unrelated families with 11 different homozygous mutations and one instance of compound heterozygosity in the WISP3 gene. It proves that this entity is not very uncommon in India.
NURSING MANAGEMENT OF PATIENT WITH KIDNEY AND URINARY SYSTEM DISORDERSRekhanjali Gupta
12 slides•16 views
Urethritis is an inflammation of the urethra, the tube that carries urine from the bladder out of the body. It's often caused by a bacterial infection, commonly a sexually transmitted infection (STI) like gonorrhea or chlamydia. Pain or burning during urination is a key symptom, along with other symptoms like urethral discharge and the frequent need to urinate.
At Dr. Akshay's DentAvenue Dental Clinic in Chembur, expert dentists Dr. Akshay Bandewar and Dr. Saudnya Bandewar are committed to delivering comprehensive dental care with a focus on advanced treatments. Dr. Akshay, a leading prosthodontist, implantologist, and dental implants periodontist with 13 years of experience, specializes in full mouth rehabilitation, crown & bridge work, and smile designing, while Dr. Saudnya, an experienced endodontist, pediatric dentist, and laser dentist with 8 years of expertise, offers specialized treatments such as root canal therapy, pediatric dental care, and laser gum treatments. From orthodontics (traditional braces & Invisalign) to cosmetic dentistry, periodontics, teeth whitening services, and more, a wide array of treatments is available. Whether it's dental implants, a smile makeover, or routine dental care, Dr. Akshay and Dr. Saudnya ensure expert solutions tailored to every patient's needs. Visit today for advanced, compassionate, and personalized dental care.
Dr. Akshay Bandewar, the Founder of Dr. Akshay's DentAvenue Dental Clinic in Chembur, is an experienced Prosthodontist and Implantologist with over 13 years of expertise. He specializes in Dental implants in Chembur, Full Mouth Rehabilitation, Smile Designing, and a variety of restorative treatments. Dr. Akshay holds an MDS in Prosthodontics (Crown, Bridge, and Implantology) from Government Dental College, Mumbai, and has honed his skills in Crown, Bridge, and Implantology over the years. His comprehensive approach ensures that every patient receives personalized care, whether it's dental implants or smile makeover treatments. As a former assistant professor at Government Dental College, Mumbai, Dr. Akshay stays at the forefront of dental advancements. His clinic is equipped with state-of-the-art technology, providing precision and efficiency in all treatments. Whether you need Dental implants in Chembur or a complete smile restoration, Dr. Akshay offers expert solutions tailored to your needs. Trust his 13+ years of experience for the best dental care. Visit Dr. Akshay at Dr. Akshay’s DentAvenue for exceptional and personalized dental treatment.
Dr. Saudnya, Co-founder of Dr. Akshay's DentAvenue Dental Clinic in Chembur, with over 8 years of experience in the dental field. As an expert in Root Canals, Crowns, Bridges, Cosmetic Dentistry, Dentures, and more, she offers exceptional care to all her patients. Dr. Saudnya is also skilled in Pediatric Dental Treatment, ensuring a gentle approach for children’s dental needs.
Tags:- dental clinic in Chembur, dentist in Chembur, implantologist in Chembur, prosthodontist in Chembur, endodontist in Chembur, cosmetic dentist in Chembur, orthodontist in Chembur, periodontist in Chembur, pediatric dentist in Chembur, best dentist in Chembur.
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
29 slides•69.3K views
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
New Drug Development in the Treatment of Ovarian Cancer: Future Perspectives
Ovarian cancer remains a major challenge in gynecologic oncology due to its late diagnosis, high relapse rate, and limited long-term treatment success. While surgery and platinum-based chemotherapy remain the mainstays of therapy, advances in molecular biology and precision medicine are transforming the treatment landscape. The future of ovarian cancer management lies in the development of targeted therapies, immunotherapy, and innovative drug delivery systems, aiming for personalized and durable outcomes.
PARP inhibitors have been among the most significant breakthroughs, particularly in patients with BRCA mutations or homologous recombination deficiency (HRD). Agents like olaparib, niraparib, and rucaparib work by exploiting defects in DNA repair mechanisms, leading to synthetic lethality in tumor cells. Their use has expanded from treatment of recurrent disease to maintenance therapy in first-line settings. Current research focuses on overcoming resistance by combining PARP inhibitors with other agents, such as immune checkpoint inhibitors, anti-angiogenic drugs, or ATR inhibitors.
Immunotherapy has had modest results in ovarian cancer so far, likely due to the immunosuppressive tumor microenvironment. However, future strategies are exploring combinations of checkpoint inhibitors (like pembrolizumab or nivolumab) with chemotherapy, PARP inhibitors, or anti-VEGF agents to enhance tumor immunogenicity. Additionally, experimental approaches such as CAR-T cells, oncolytic viruses, and cancer vaccines are under investigation.
Angiogenesis inhibitors, such as bevacizumab, have shown clinical benefit and are approved in both first-line and recurrent disease settings. Novel anti-angiogenic agents and combination regimens aim to further exploit the tumor’s reliance on blood supply while improving drug delivery and immune cell access.
Emerging therapies like antibody-drug conjugates (ADCs) offer targeted cytotoxicity by linking monoclonal antibodies to chemotherapy agents. Mirvetuximab soravtansine, targeting folate receptor alpha (FRα), is a leading ADC showing promise in platinum-resistant ovarian cancer.
Epigenetic therapies are another exciting avenue. Agents that modify DNA methylation or histone acetylation may reverse chemoresistance and sensitize tumors to other treatments. Similarly, targeting hormonal pathways and metabolic dependencies (like glucose and lipid metabolism) offers potential in select subtypes.
Looking ahead, the integration of genomic profiling, biomarkers, and artificial intelligence is driving a shift toward precision oncology. Techniques like liquid biopsy allow real-time monitoring of tumor evolution and therapeutic response. Moreover, advances in nanotechnology and local drug delivery systems are improving the precision and tolerability of therapies.
In conclusion, the future of ovarian cancer treatment is bright, with a strong focus on indi
Title: Iron and Hemoglobin Metabolism
Lecturer: Dr. Faiza
Assistant Professor of Physiology
Institution: [Your Institution's Name]
Description:
This lecture provides a thorough exploration of the essential processes involved in iron metabolism and the synthesis, function, and types of hemoglobin, with a specific focus on their roles in erythropoiesis. Dr. Faiza, Assistant Professor of Physiology, takes students through the biochemistry and physiology underlying these critical aspects of human biology. The lecture also delves into the importance of vitamin B12 and folic acid in red blood cell (RBC) maturation and the impact of iron metabolism on erythropoiesis.
Key learning objectives include:
Understanding the crucial roles of Vitamin B12 and Folic Acid in RBC maturation and their relationship with DNA synthesis.
Identifying the synthesis process and functions of Hemoglobin.
Analyzing the different types of hemoglobin and their relevance at various stages of human development.
Exploring iron metabolism, its role in the production of hemoglobin, and its essential involvement in erythropoiesis.
Discussing the metabolism of bilirubin and its clinical implications, including the development of jaundice.
The presentation also covers the important aspects of hemoglobin electrophoresis, the reversible binding of oxygen to hemoglobin, and its ability to transport carbon dioxide and nitric oxide, contributing to blood pressure regulation. Additionally, the lecture touches on metabolic disorders such as methemoglobinemia, where the iron in hemoglobin is oxidized, impairing oxygen binding.
Topics Covered:
Vitamin B12 and Folic Acid in RBC Maturation: The lecture emphasizes the role of these vitamins in DNA synthesis, with a focus on how deficiencies can lead to macrocytic anemia.
Hemoglobin Structure and Synthesis: Understanding the components of hemoglobin, including the globin chains and heme groups, and their formation process.
Types of Hemoglobin: Insight into embryonic, fetal, and adult hemoglobins, including the clinical significance of variants like HbS (sickle cell hemoglobin).
Iron Metabolism: A detailed look at how iron is absorbed, transported, and stored in the body, as well as its critical role in the production of hemoglobin.
Bilirubin Metabolism: The process of bilirubin production from RBC breakdown, including its implications for jaundice.
This lecture is designed to provide students with a deep understanding of these fundamental physiological processes, preparing them for clinical challenges and further studies in the field of hematology and physiology.
A vivid description of the acetate mevalonate pathway, a gateway for many secondary metabolites among which are volatile oils, saponins, and cardiac glycosides.
This particular document shows the origins of monoterpenes, diterpenes, sesquiterpenoids, triterpenoids and tetraterpenoids.
Ethical Concerns in Regenerative Medicine and Tissue Engineering: A Course Le...ajefferi
10 slides•231 views
A course learning resource for a new proposed course on ethical concerns in regenerative medicine and tissue engineering. Created by postgraduate students at University of Edinburgh.
Spinal biomechanics involves the regional features of the vertebrae, intervertebral discs, ligaments, facet joints and muscles. The role of these structures individually and in concert in relation to injuries.
Dr Aliya S.M
GIST , pathophysiology , diagnosis and management dr. amrish .pptxDr. Amrish Yadav
35 slides•66 views
1) Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the Gl tract that arise from interstitial cells of Cajal.
2) GISTs most commonly occur in the stomach and small intestine and present with Gl bleeding, abdominal pain, or mass.
3) Diagnostic workup includes CT, endoscopy, and biopsy to establish a diagnosis, assess resectability, and identify mutations for targeted therapy.
4) Complete surgical resection is the main treatment, while adjuvant imatinib therapy helps maintain remission and unresectable tumors may be downstaged with neoadjuvant imatinib
Bone mineral density measurements in nuclear medicineMiadAlsulami
39 slides•256 views
In every Nuclear Medicine department, DEXA scans are important and performed daily. It's crucial for us to accurately understand and interpret these scans.
Biophysics – Unit 01: Thermodynamics
This unit introduces the fundamental principles of thermodynamics and their application in biological and physiological systems. It explores how energy is exchanged and transformed in the human body, forming the basis of many critical clinical processes.
Key Concepts Covered:
System & Surroundings: Open, closed, and isolated systems relevant to physiological environments (e.g., respiratory system as an open system).
Zeroth Law: Basis for clinical thermometry and body temperature regulation.
First Law of Thermodynamics (Law of Energy Conservation): Application in calorimetry, metabolic rate calculation, and ATP energy balance.
Second Law of Thermodynamics: Directionality of biological processes, entropy, and energy efficiency in muscle contraction and enzymatic activity.
Third Law: Conceptual relevance in absolute zero and physiological limits.
Clinical Applications:
Energy transformations during cellular respiration
Thermal regulation and homeostasis in patients
Bioenergetics in critical care (e.g., post-operative energy needs, fever metabolism)
Use of thermodynamic principles in medical devices (ventilators, incubators, dialysis machines)
Negligence & Medical Ethics – The Unspoken Pandemic Presented by Dr. Kadiyali M Srivatsa
Every day, patients walk into clinics, trusting someone will care for them. But what if I told you…
that medical errors are now the third leading cause of death in the world?
Yes—after heart disease and cancer.
And the tragedy?
Most of these deaths are preventable.
🎬 Scene 2: Medical Negligence – A Global Crisis
On Screen:
⚠️ FACT: 2.6 million deaths annually are linked to medical errors – WHO
Narration:
According to the World Health Organization,
over 2.6 million people die every year due to unsafe medical care.
In high-income countries,
1 in 10 patients is harmed while receiving hospital care.
In low- and middle-income countries…
the number is likely even higher, but underreported.
This… is a silent pandemic.
Act of Commission vs. Omission
Negligence isn’t always about what’s done. It’s often about what is not done.
Doing what shouldn’t be done. Or…
failing to do what must be done.
Both destroy lives.
Nurses Acting as Doctors
Untrained, Unsupervised, Unethical. In some systems, nurses with only 6 months of training diagnose, prescribe, and manage patients without supervision.
This is not progress. It’s cost-cutting at the cost of lives.
Since 2006, hospitals in the UK began replacing doctors with “Independent Nurse Practitioners and prescriber.”
And what happened?
Avoidable deaths doubled. Medical litigation rose to £1.5 billion. Hospitals started collapsing under the weight of compensation claims.
Real Cases – Real Suffering
On Screen:
🚨 True Stories That Shake the Soul
Narration:
A nurse tells a 23-year-old woman with yellow eyes “It’s just a flu. Take paracetamol.” Two days later, she’s in liver failure.
A young man misdiagnosed with shingles actually has septicemia—He collapses in shock. Survives—but just barely.
A toddler with pneumonia is sent home. Told to return after the weekend.
She nearly dies. These are not accidents.
These are acts of negligence. And behind every mistake… is a family left grieving.
Why did I create Dr. Maya GPT?
Dr. Maya GPT – A Global Guardian for Patient Safety. I could no longer bear to watch patients suffer due to systemic negligence,
corporate cost-cutting, and ego-driven medicine.
Dr. Maya is not a replacement for doctors.
It is a guide.
A safety net.
An AI-powered guardian that helps people identify when to seek help—
and most importantly, whom to trust.
The Ethical Compass – Diligence - A Universal Virtue Across Faiths
Whether it's the teachings of the Bible, the Quran, the Gita, or the Dhammapada -they all echo one truth:
“Act with diligence.” That means effort. Integrity.
And doing the right thing—even when no one is watching.
This presentation is based on the series and flowcharts decisions to be made and of methods when dealing with a case of tooth avulsion in children (more specifically) and adults.
All references have been enumerated in the last slides.
Hit LIKE if you found this content helpful.
Genes are formed by the order of the nitrogenous bases present in the DNA which is crucial for protein synthesis. RNA is another nucleic acid that translates genetic information into proteins from DNA. The nucleotides are linked together for the formation of two long strands. genomics, which encompasses the examination of an organism's entire set of genetic material, including DNA and RNA.
by Dr Aliya S.M
BUMHS,QTA
Spondyloepiphyseal dysplasia is a mimicker of arthritisRitasman Baisya
11 slides•72 views
Musculoskeletal involvement in children is often challenging, with a wide range of benign conditions, such as growing pain, to severe systemic diseases. Spondylo-epiphyseal dysplasia (SED) is an autosomal recessive disease of the skeletal system that often mimics juvenile idiopathic arthritis (JIA) with no response to anti-rheumatic therapy.
Case - A young male, 22 years of age, presented with a history of pain in his upper and lower back and multiple small and large joints since five years of age. He denied any morning stiffness or increased nocturnal pain. Previously, he was treated outside as juvenile idiopathic arthritis with methotrexate, sulfasalazine and injection Adalimumab. However, his mother denied any symptomatic improvement of his pain. On examination, his growth was stunted with significant kyphoscoliosis. (Figure 1 ) He had an antalgic gait with exaggerated lumbar lordosis. He had mild tenderness in both hips, knees and ankles with flexion contracture and bony swelling at bilateral proximal & distal interphalangeal joints (PIP and DIP), referred to as camptodactyly. (Figure 2 ) His cervical and lumbar movement was severely restricted, with bilateral hip movement restricted. Laboratory investigation showed normal ESR CRP. Rheumatoid factor was low titre positive, anti-CCP antibody and HLA-B27 by PCR were negative. His skeletal radiographic images showed platyspondyly in the thoracolumbar spine, epiphyseal widening in MCP and IP joints with ovoid carpal bones (Figure 3), platyspondyly in the thoracolumbar spine (Figure 4) , hip joint sclerosis . (Figure 5 ) His diagnosis was reconsidered as spondyloepiphyseal dysplasia (SED) . He was started with extensive physiotherapy and symptomatic pain relief treatment and noticed improvement in his pain and quality of life.
Brief discussion - SED predominantly involves articular cartilage, which results in joint stiffness and epiphyseal enlargement. Typically starting at 2-8 years of age, they manifest with pain, stiffness and swelling of extremity joints. (1) On examination, the swelling is predominantly bony without any evidence of inflammation. Over time, the large joints and the spine get involved, causing significant joint contractures, gait abnormality, kyphoscoliosis, abnormal posture and poor quality of life. There are reported cases where SED have been misdiagnosed as JIA with no response to immunomodulatory treatment. (1,2) SED's radiological features differ from JIA, with platyspondyly being an early finding in the skeletal image, epiphyseal enlargement, and lack of destructive joint erosions. Though SED is considered a rare entity, one large study by Dalal et al. (3) reported 35 cases of SED from 25 unrelated families with 11 different homozygous mutations and one instance of compound heterozygosity in the WISP3 gene. It proves that this entity is not very uncommon in India.
NURSING MANAGEMENT OF PATIENT WITH KIDNEY AND URINARY SYSTEM DISORDERSRekhanjali Gupta
12 slides•16 views
Urethritis is an inflammation of the urethra, the tube that carries urine from the bladder out of the body. It's often caused by a bacterial infection, commonly a sexually transmitted infection (STI) like gonorrhea or chlamydia. Pain or burning during urination is a key symptom, along with other symptoms like urethral discharge and the frequent need to urinate.
At Dr. Akshay's DentAvenue Dental Clinic in Chembur, expert dentists Dr. Akshay Bandewar and Dr. Saudnya Bandewar are committed to delivering comprehensive dental care with a focus on advanced treatments. Dr. Akshay, a leading prosthodontist, implantologist, and dental implants periodontist with 13 years of experience, specializes in full mouth rehabilitation, crown & bridge work, and smile designing, while Dr. Saudnya, an experienced endodontist, pediatric dentist, and laser dentist with 8 years of expertise, offers specialized treatments such as root canal therapy, pediatric dental care, and laser gum treatments. From orthodontics (traditional braces & Invisalign) to cosmetic dentistry, periodontics, teeth whitening services, and more, a wide array of treatments is available. Whether it's dental implants, a smile makeover, or routine dental care, Dr. Akshay and Dr. Saudnya ensure expert solutions tailored to every patient's needs. Visit today for advanced, compassionate, and personalized dental care.
Dr. Akshay Bandewar, the Founder of Dr. Akshay's DentAvenue Dental Clinic in Chembur, is an experienced Prosthodontist and Implantologist with over 13 years of expertise. He specializes in Dental implants in Chembur, Full Mouth Rehabilitation, Smile Designing, and a variety of restorative treatments. Dr. Akshay holds an MDS in Prosthodontics (Crown, Bridge, and Implantology) from Government Dental College, Mumbai, and has honed his skills in Crown, Bridge, and Implantology over the years. His comprehensive approach ensures that every patient receives personalized care, whether it's dental implants or smile makeover treatments. As a former assistant professor at Government Dental College, Mumbai, Dr. Akshay stays at the forefront of dental advancements. His clinic is equipped with state-of-the-art technology, providing precision and efficiency in all treatments. Whether you need Dental implants in Chembur or a complete smile restoration, Dr. Akshay offers expert solutions tailored to your needs. Trust his 13+ years of experience for the best dental care. Visit Dr. Akshay at Dr. Akshay’s DentAvenue for exceptional and personalized dental treatment.
Dr. Saudnya, Co-founder of Dr. Akshay's DentAvenue Dental Clinic in Chembur, with over 8 years of experience in the dental field. As an expert in Root Canals, Crowns, Bridges, Cosmetic Dentistry, Dentures, and more, she offers exceptional care to all her patients. Dr. Saudnya is also skilled in Pediatric Dental Treatment, ensuring a gentle approach for children’s dental needs.
Tags:- dental clinic in Chembur, dentist in Chembur, implantologist in Chembur, prosthodontist in Chembur, endodontist in Chembur, cosmetic dentist in Chembur, orthodontist in Chembur, periodontist in Chembur, pediatric dentist in Chembur, best dentist in Chembur.
AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork
Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.
Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.
PEPSICO Presentation to CAGNY Conference Feb 2024Neil Kimberley
PepsiCo provided a safe harbor statement noting that any forward-looking statements are based on currently available information and are subject to risks and uncertainties. It also provided information on non-GAAP measures and directing readers to its website for disclosure and reconciliation. The document then discussed PepsiCo's business overview, including that it is a global beverage and convenient food company with iconic brands, $91 billion in net revenue in 2023, and nearly $14 billion in core operating profit. It operates through a divisional structure with a focus on local consumers.
Content Methodology: A Best Practices Report (Webinar)contently
This document provides an overview of content methodology best practices. It defines content methodology as establishing objectives, KPIs, and a culture of continuous learning and iteration. An effective methodology focuses on connecting with audiences, creating optimal content, and optimizing processes. It also discusses why a methodology is needed due to the competitive landscape, proliferation of channels, and opportunities for improvement. Components of an effective methodology include defining objectives and KPIs, audience analysis, identifying opportunities, and evaluating resources. The document concludes with recommendations around creating a content plan, testing and optimizing content over 90 days.
How to Prepare For a Successful Job Search for 2024Albert Qian
The document provides guidance on preparing a job search for 2024. It discusses the state of the job market, focusing on growth in AI and healthcare but also continued layoffs. It recommends figuring out what you want to do by researching interests and skills, then conducting informational interviews. The job search should involve building a personal brand on LinkedIn, actively applying to jobs, tailoring resumes and interviews, maintaining job hunting as a habit, and continuing self-improvement. Once hired, the document advises setting new goals and keeping skills and networking active in case of future opportunities.
A report by thenetworkone and Kurio.
The contributing experts and agencies are (in an alphabetical order): Sylwia Rytel, Social Media Supervisor, 180heartbeats + JUNG v MATT (PL), Sharlene Jenner, Vice President - Director of Engagement Strategy, Abelson Taylor (USA), Alex Casanovas, Digital Director, Atrevia (ES), Dora Beilin, Senior Social Strategist, Barrett Hoffher (USA), Min Seo, Campaign Director, Brand New Agency (KR), Deshé M. Gully, Associate Strategist, Day One Agency (USA), Francesca Trevisan, Strategist, Different (IT), Trevor Crossman, CX and Digital Transformation Director; Olivia Hussey, Strategic Planner; Simi Srinarula, Social Media Manager, The Hallway (AUS), James Hebbert, Managing Director, Hylink (CN / UK), Mundy Álvarez, Planning Director; Pedro Rojas, Social Media Manager; Pancho González, CCO, Inbrax (CH), Oana Oprea, Head of Digital Planning, Jam Session Agency (RO), Amy Bottrill, Social Account Director, Launch (UK), Gaby Arriaga, Founder, Leonardo1452 (MX), Shantesh S Row, Creative Director, Liwa (UAE), Rajesh Mehta, Chief Strategy Officer; Dhruv Gaur, Digital Planning Lead; Leonie Mergulhao, Account Supervisor - Social Media & PR, Medulla (IN), Aurelija Plioplytė, Head of Digital & Social, Not Perfect (LI), Daiana Khaidargaliyeva, Account Manager, Osaka Labs (UK / USA), Stefanie Söhnchen, Vice President Digital, PIABO Communications (DE), Elisabeth Winiartati, Managing Consultant, Head of Global Integrated Communications; Lydia Aprina, Account Manager, Integrated Marketing and Communications; Nita Prabowo, Account Manager, Integrated Marketing and Communications; Okhi, Web Developer, PNTR Group (ID), Kei Obusan, Insights Director; Daffi Ranandi, Insights Manager, Radarr (SG), Gautam Reghunath, Co-founder & CEO, Talented (IN), Donagh Humphreys, Head of Social and Digital Innovation, THINKHOUSE (IRE), Sarah Yim, Strategy Director, Zulu Alpha Kilo (CA).
Trends In Paid Search: Navigating The Digital Landscape In 2024Search Engine Journal
The search marketing landscape is evolving rapidly with new technologies, and professionals, like you, rely on innovative paid search strategies to meet changing demands.
It’s important that you’re ready to implement new strategies in 2024.
Check this out and learn the top trends in paid search advertising that are expected to gain traction, so you can drive higher ROI more efficiently in 2024.
You’ll learn:
- The latest trends in AI and automation, and what this means for an evolving paid search ecosystem.
- New developments in privacy and data regulation.
- Emerging ad formats that are expected to make an impact next year.
Watch Sreekant Lanka from iQuanti and Irina Klein from OneMain Financial as they dive into the future of paid search and explore the trends, strategies, and technologies that will shape the search marketing landscape.
If you’re looking to assess your paid search strategy and design an industry-aligned plan for 2024, then this webinar is for you.
5 Public speaking tips from TED - Visualized summarySpeakerHub
From their humble beginnings in 1984, TED has grown into the world’s most powerful amplifier for speakers and thought-leaders to share their ideas. They have over 2,400 filmed talks (not including the 30,000+ TEDx videos) freely available online, and have hosted over 17,500 events around the world.
With over one billion views in a year, it’s no wonder that so many speakers are looking to TED for ideas on how to share their message more effectively.
The article “5 Public-Speaking Tips TED Gives Its Speakers”, by Carmine Gallo for Forbes, gives speakers five practical ways to connect with their audience, and effectively share their ideas on stage.
Whether you are gearing up to get on a TED stage yourself, or just want to master the skills that so many of their speakers possess, these tips and quotes from Chris Anderson, the TED Talks Curator, will encourage you to make the most impactful impression on your audience.
See the full article and more summaries like this on SpeakerHub here: https://speakerhub.com/blog/5-presentation-tips-ted-gives-its-speakers
See the original article on Forbes here:
http://www.forbes.com/forbes/welcome/?toURL=http://www.forbes.com/sites/carminegallo/2016/05/06/5-public-speaking-tips-ted-gives-its-speakers/&refURL=&referrer=#5c07a8221d9b
ChatGPT and the Future of Work - Clark Boyd Clark Boyd
Everyone is in agreement that ChatGPT (and other generative AI tools) will shape the future of work. Yet there is little consensus on exactly how, when, and to what extent this technology will change our world.
Businesses that extract maximum value from ChatGPT will use it as a collaborative tool for everything from brainstorming to technical maintenance.
For individuals, now is the time to pinpoint the skills the future professional will need to thrive in the AI age.
Check out this presentation to understand what ChatGPT is, how it will shape the future of work, and how you can prepare to take advantage.
The document provides career advice for getting into the tech field, including:
- Doing projects and internships in college to build a portfolio.
- Learning about different roles and technologies through industry research.
- Contributing to open source projects to build experience and network.
- Developing a personal brand through a website and social media presence.
- Networking through events, communities, and finding a mentor.
- Practicing interviews through mock interviews and whiteboarding coding questions.
Google's Just Not That Into You: Understanding Core Updates & Search IntentLily Ray
1. Core updates from Google periodically change how its algorithms assess and rank websites and pages. This can impact rankings through shifts in user intent, site quality issues being caught up to, world events influencing queries, and overhauls to search like the E-A-T framework.
2. There are many possible user intents beyond just transactional, navigational and informational. Identifying intent shifts is important during core updates. Sites may need to optimize for new intents through different content types and sections.
3. Responding effectively to core updates requires analyzing "before and after" data to understand changes, identifying new intents or page types, and ensuring content matches appropriate intents across video, images, knowledge graphs and more.
A brief introduction to DataScience with explaining of the concepts, algorithms, machine learning, supervised and unsupervised learning, clustering, statistics, data preprocessing, real-world applications etc.
It's part of a Data Science Corner Campaign where I will be discussing the fundamentals of DataScience, AIML, Statistics etc.
Time Management & Productivity - Best PracticesVit Horky
Here's my presentation on by proven best practices how to manage your work time effectively and how to improve your productivity. It includes practical tips and how to use tools such as Slack, Google Apps, Hubspot, Google Calendar, Gmail and others.
The six step guide to practical project managementMindGenius
The six step guide to practical project management
If you think managing projects is too difficult, think again.
We’ve stripped back project management processes to the
basics – to make it quicker and easier, without sacrificing
the vital ingredients for success.
“If you’re looking for some real-world guidance, then The Six Step Guide to Practical Project Management will help.”
Dr Andrew Makar, Tactical Project Management
Unlocking the Power of ChatGPT and AI in Testing - A Real-World Look, present...Applitools
During this webinar, Anand Bagmar demonstrates how AI tools such as ChatGPT can be applied to various stages of the software development life cycle (SDLC) using an eCommerce application case study. Find the on-demand recording and more info at https://applitools.info/b59
Key takeaways:
• Learn how to use ChatGPT to add AI power to your testing and test automation
• Understand the limitations of the technology and where human expertise is crucial
• Gain insight into different AI-based tools
• Adopt AI-based tools to stay relevant and optimize work for developers and testers
* ChatGPT and OpenAI belong to OpenAI, L.L.C.
The document discusses various AI tools from OpenAI like GPT-3 and DALL-E 2, as well as ChatGPT. It explores how search engines are using AI and things to consider around AI-generated content. Potential SEO uses of ChatGPT are also presented, such as generating content at scale, conducting topic research, and automating basic coding tasks. The document encourages further reading on using ChatGPT for SEO purposes.
More than Just Lines on a Map: Best Practices for U.S Bike Routes
This session highlights best practices and lessons learned for U.S. Bike Route System designation, as well as how and why these routes should be integrated into bicycle planning at the local and regional level.
Presenters:
Presenter: Kevin Luecke Toole Design Group
Co-Presenter: Virginia Sullivan Adventure Cycling Association
